Description

9A-Fluoro-11, 6A, 17A, 21-Tetrahydroxy-Pregna-4-Ene-3, 20-Dione is a fluorinated steroid derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate for creating novel corticosteroid analogs with potentially enhanced therapeutic profiles. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of specialized anti-inflammatory and immunosuppressive agents. The precise control over its stereochemistry and purity is critical for downstream application success.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel fluorinated corticosteroids.
• Research & Development: Used in medicinal chemistry programs to study structure-activity relationships (SAR) of steroid hormones.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).
• Biochemical Research: Applied in studies investigating glucocorticoid receptor binding and modulation.

Basic Information

Product Name	9A-Fluoro-11, 6A, 17A, 21-Tetrahydroxy-Pregna-4-Ene-3, 20-Dione
CAS No.	2022-55-1
Molecular Formula	C21H27FO6
Molecular Weight	394.44 g/mol
Synonyms	9α-Fluoro-11β,17α,21-Trihydroxy-6α-methylpregna-4-ene-3,20-dione; 6α-Methyl-9α-fluoroprednisolone; 9α-Fluoro-6α-methylprednisolone; Fluormethylprednisolon; 6α-Methyl-9α-fluoro-δ1-hydrocortisone; 9α-Fluoro-6α-methyl-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione; 6α-Methyl-9α-fluoroprednisolone
EINECS	Contact for details

Quality Control

Our 9A-Fluoro-11, 6A, 17A, 21-Tetrahydroxy-Pregna-4-Ene-3, 20-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.