Description

3-(Trifluoromethyl)Phenacyl Bromide is a versatile and highly reactive organic bromide building block, essential for advanced synthetic chemistry. Its core value lies in the phenacyl bromide moiety, which serves as an excellent precursor for heterocyclic synthesis and a key intermediate in the development of complex molecules. This compound is particularly needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for constructing trifluoromethyl-substituted aromatic frameworks.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing the biologically active trifluoromethyl group.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the CF₃ group enhances metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of novel organic electronic materials, liquid crystals, and polymers with tailored properties.
• Heterocyclic Chemistry: A crucial starting material for the construction of various nitrogen- and oxygen-containing heterocycles, such as oxazoles and imidazoles.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes due to its reactive bromine handle.

Basic Information

Product Name	3-(Trifluoromethyl)Phenacyl Bromide
CAS No.	2003-10-3
Molecular Formula	C₉H₆BrF₃O
Molecular Weight	267.04 g/mol
Synonyms	2-Bromo-1-[3-(trifluoromethyl)phenyl]ethanone; 3'-Trifluoromethylphenacyl Bromide; α-Bromo-3'-(trifluoromethyl)acetophenone; 1-(3-(Trifluoromethyl)phenyl)-2-bromoethanone; 2-Bromo-3'-trifluoromethylacetophenone; 3-(Trifluoromethyl)phenacylbromide; ω-Bromo-3'-trifluoromethylacetophenone
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Phenacyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to handle and store the material under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.