Description

Clocinizine is a piperazine derivative with significant pharmacological activity, primarily recognized for its antihistaminic and calcium channel blocking properties. This compound is crucial for research and development in the pharmaceutical sector, offering a versatile scaffold for creating new therapeutic agents. It is particularly valuable for researchers and manufacturers in the pharmaceutical and life sciences industries focused on neuropharmacology and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced drug candidates targeting various receptor systems.
• Neuropharmacological Research: Used in preclinical studies to investigate mechanisms related to histamine H1-receptor antagonism and calcium influx modulation.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic & Institutional Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) of piperazine-based compounds.
• Chemical Synthesis: Acts as a precursor for the development of novel chemical entities with potential anti-allergic or vasodilatory effects.

Basic Information

Product Name	Clocinizine
CAS No.	298-55-5
Molecular Formula	C21H27ClN2
Molecular Weight	342.91 g/mol
Synonyms	1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine; 1-Benzhydryl-4-cinnamylpiperazine; Cinnarizine Impurity A; Cinnarizine Related Compound A; (±)-Clocinizine; Clocinizine (Cinnarizine Impurity A); NSC 113926; 1-Cinnamyl-4-(diphenylmethyl)piperazine
EINECS	206-073-6

Quality Control

Our Clocinizine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to meet the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.