Description

6-Ethoxy-2,3,4-Trifluorophenylacetonitrile is a high-value fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both an ethoxy group and multiple fluorine atoms, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated components for advanced display technologies.
• Organic Electronics: Employed in the synthesis of electron-deficient units for organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: Used as a model compound for studying the effects of polyfluorination on aromatic system reactivity.

Basic Information

Product Name	6-Ethoxy-2,3,4-Trifluorophenylacetonitrile
CAS No.	1980053-73-3
Molecular Formula	C10H7F3N1O1
Molecular Weight	207.16 g/mol
Synonyms	2-(6-Ethoxy-2,3,4-trifluorophenyl)acetonitrile; (6-Ethoxy-2,3,4-trifluorophenyl)acetonitrile; 2,3,4-Trifluoro-6-ethoxyphenylacetonitrile; 6-Ethoxy-2,3,4-trifluorobenzeneacetonitrile; α-Cyano-6-ethoxy-2,3,4-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 6-Ethoxy-2,3,4-Trifluorophenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. The compound is moisture-sensitive (hygroscopic); ensure containers are sealed under an inert atmosphere after opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.