Description

2-Fluoro-3-Methoxy-6-Nitrobenzonitrile is a high-purity, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. Its unique substitution pattern makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for researchers and manufacturers in pharmaceutical R&D, agrochemical discovery, and advanced material science seeking to introduce specific fluorine, methoxy, and nitro functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging the fluorine and nitro groups for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Functional Material Research: Employed in the synthesis of organic electronic materials, such as OLED and OFET components, due to its electron-withdrawing nitrile group.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for biological imaging and diagnostics.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	2-Fluoro-3-Methoxy-6-Nitrobenzonitrile
CAS No.	1936542-19-6
Molecular Formula	C8H5FN2O3
Molecular Weight	196.14 g/mol
Synonyms	2-Fluoro-3-methoxy-6-nitrobenzonitrile; 6-Nitro-2-fluoro-3-methoxybenzonitrile; Benzonitrile, 2-fluoro-3-methoxy-6-nitro-; 3-Methoxy-2-fluoro-6-nitrobenzonitrile; 2-Fluoro-6-nitro-3-methoxybenzonitrile; 1936542-19-6; 2-F-3-MeO-6-NO2-BnCN
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Methoxy-6-Nitrobenzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.