Description

2-(2,6-Difluorophenyl)Malononitrile is a high-value fluorinated aromatic building block and key synthetic intermediate. This compound is prized for its versatile reactivity, particularly in the construction of complex heterocyclic systems and advanced functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing fluorinated heterocycles like pyrimidines and pyridines.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluorophenyl moiety enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized fluorinated dyes and pigments that offer superior lightfastness and color properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Cyclization Reactions: Utilized in the formation of various nitrogen-containing heterocycles, such as pyrazoles and pyrimidines, which are common scaffolds in medicinal chemistry.

Basic Information

Product Name	2-(2,6-Difluorophenyl)Malononitrile
CAS No.	1936181-34-8
Molecular Formula	C9H4F2N2
Molecular Weight	178.14 g/mol
Synonyms	2,6-Difluorobenzylidene Malononitrile; (2,6-Difluorophenyl)Propanedinitrile; 2-(2,6-Difluorobenzylidene)Malononitrile; Malononitrile, (2,6-difluorophenyl)-; 2,6-Difluoro-α-(cyanomethylene)benzeneacetonitrile; 2-(2,6-Difluorophenyl)-1,3-propanedinitrile; 2,6-Difluorobenzalmalononitrile
EINECS	Contact for details

Quality Control

Our 2-(2,6-Difluorophenyl)Malononitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.