Description

4-Amino-5-Bromo-2-Fluoro-Benzonitrile is a high-value, multi-functional aromatic nitrile building block. This compound matters for its unique substitution pattern, which makes it a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the fluorine and bromine substituents for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers due to its conjugated system.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific custom synthesis projects.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes in diagnostic and research applications.

Basic Information

Product Name	4-Amino-5-Bromo-2-Fluoro-Benzonitrile
CAS No.	1934940-89-2
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	5-Bromo-2-fluoro-4-aminobenzonitrile; 2-Fluoro-4-amino-5-bromobenzonitrile; 4-Amino-5-bromo-2-fluorobenzonitrile; Benzonitrile, 4-amino-5-bromo-2-fluoro-; 1934940-89-2; 5-Bromo-2-fluoro-4-cyanoaniline
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Bromo-2-Fluoro-Benzonitrile is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.