Description

cis-(3-(Trifluoromethyl)Piperidin-2-Yl)Methanol (Wx601675) is a high-value, fluorinated piperidine derivative serving as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and a hydroxymethyl substituent on the piperidine ring, makes it indispensable for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals that require fluorinated components for specific performance characteristics.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	cis-(3-(Trifluoromethyl)Piperidin-2-Yl)Methanol (Wx601675)
CAS No.	1932571-29-3
Molecular Formula	C7H12F3NO
Molecular Weight	183.17 g/mol
Synonyms	(2S,3R)-3-(Trifluoromethyl)piperidine-2-methanol; (2S,3R)-3-(Trifluoromethyl)-2-piperidinemethanol; cis-3-(Trifluoromethyl)-2-piperidinemethanol; WX-601675; (2S,3R)-rel-3-(Trifluoromethyl)-2-piperidinemethanol; 2-Piperidinemethanol, 3-(trifluoromethyl)-, (2S,3R)-rel-
EINECS	Contact for details

Quality Control

Every batch of cis-(3-(Trifluoromethyl)Piperidin-2-Yl)Methanol is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are aligned with ICH guidelines for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) providing purity, chiral purity, and impurity profiles from validated methods (HPLC, GC, NMR) is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.