Description

cis-3-Amino-1-(Trifluoromethyl)Cyclohexan-1-Ol is a high-value, chiral building block featuring both an amino and a hydroxyl group on a cyclohexane scaffold with a trifluoromethyl substituent. This unique structure makes it a critical intermediate for the synthesis of advanced pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and metabolic disease therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with unique surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme inhibition.

Basic Information

Product Name	cis-3-Amino-1-(Trifluoromethyl)Cyclohexan-1-Ol
CAS No.	1932101-55-7
Molecular Formula	C7H12F3NO
Molecular Weight	183.17 g/mol
Synonyms	1-(Trifluoromethyl)-3-aminocyclohexan-1-ol (cis); cis-3-Amino-1-(trifluoromethyl)cyclohexanol; 3-Amino-1-(trifluoromethyl)cyclohexanol; 3-Amino-α,α,α-trifluoro-1-cyclohexanemethanol; (1R,3S)-3-Amino-1-(trifluoromethyl)cyclohexan-1-ol (enantiomer); Cyclohexanol, 3-amino-1-(trifluoromethyl)-, cis-; CAS 1932101-55-7
EINECS	Contact for details

Quality Control

Our cis-3-Amino-1-(Trifluoromethyl)Cyclohexan-1-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (HPLC), enantiomeric excess, and impurities is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.