Description

(Des-Gly10,D-Ser4,D-Trp6,Pro-Nhet9)-Lhrh CAS NO 1926163-22-5 is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), engineered with specific amino acid modifications to enhance its stability and biological activity. This compound is critical for advanced research and development in endocrinology and oncology, offering a valuable tool for studying hormone-dependent processes. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel hormone therapies and targeted cancer treatments.
• Endocrinology Studies: Used in vitro and in vivo to investigate the mechanisms of the hypothalamic-pituitary-gonadal axis and the regulation of gonadotropin secretion.
• Oncology Research: Employed in preclinical studies for hormone-dependent cancers, such as prostate and breast cancer, to evaluate the efficacy of LHRH analog-based therapies.
• Biochemical Assay Development: Functions as a critical component in the development and validation of immunoassays, receptor binding assays, and other diagnostic tests.
• Peptide Chemistry & Drug Design: Provides a model compound for studying structure-activity relationships (SAR) and for the synthesis of new peptide derivatives with optimized properties.

Basic Information

Product Name	(Des-Gly10,D-Ser4,D-Trp6,Pro-Nhet9)-Lhrh
CAS No.	1926163-22-5
Molecular Formula	C58H78N16O12
Molecular Weight	1151.3 g/mol
Synonyms	Des-Gly10,D-Ser(tBu)4,D-Trp6,Pro-NHEt9-LHRH; LHRH Analog (Des-Gly10,D-Ser4,D-Trp6,Pro-Nhet9); Gonadorelin Analog; Luteinizing Hormone-Releasing Hormone Derivative; pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt; [Des-Gly10, D-Ser4, D-Trp6, Pro-NHEt9]-LHRH; Synthetic LHRH Agonist/Antagonist Analog
EINECS	Contact for details

Quality Control

Our (Des-Gly10,D-Ser4,D-Trp6,Pro-Nhet9)-Lhrh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant after each use to maintain integrity. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content (Amino Acid Analysis)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.