Description

Benzonitrile, 5-Bromo-2-Chloro-4-Fluoro- is a high-purity, multi-substituted aromatic nitrile building block of significant interest in advanced organic synthesis. Its precise halogenation pattern makes it a critical intermediate for constructing complex molecular architectures where specific regiochemistry is required. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the bromo, chloro, and fluoro substituents confer specific biological activity.
• Ligand and Catalyst Development: Employed as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Benzonitrile, 5-Bromo-2-Chloro-4-Fluoro-
CAS No.	1892285-40-3
Molecular Formula	C7H2BrClFN
Molecular Weight	234.45 g/mol
Synonyms	5-Bromo-2-chloro-4-fluorobenzonitrile; 2-Chloro-5-bromo-4-fluorobenzonitrile; 4-Fluoro-5-bromo-2-chlorobenzonitrile; Benzonitrile, 5-bromo-2-chloro-4-fluoro-; 3-Bromo-6-chloro-4-cyanobenzene fluoride; (5-Bromo-2-chloro-4-fluorophenyl)carbonitrile; 2-Chloro-4-fluoro-5-bromobenzonitrile
EINECS	Contact for details

Quality Control

Every batch of Benzonitrile, 5-Bromo-2-Chloro-4-Fluoro- is produced and analyzed under a strict quality management system. We guarantee high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC-MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.