Description

Methyl 4-(2,6-Dimethylmorpholin-4-Yl)-2,3,5-Trifluorobenzoate is a high-value, fluorinated benzoate derivative featuring a substituted morpholine ring, designed for advanced synthetic applications. This compound is a critical pharmaceutical intermediate and building block in the development of novel active ingredients, particularly in medicinal chemistry. It is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate complex fluorinated motifs into their target molecules.

Application

This fluorinated morpholine-benzoate ester serves as a sophisticated synthetic precursor. Its primary and potential applications include:

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atoms and morpholine moiety can enhance biological activity and environmental stability.
• Material Science Chemistry: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced materials with tailored properties.
• Ligand and Catalyst Development: The nitrogen and oxygen atoms in the morpholine ring make it a candidate for constructing novel ligands in catalytic systems.
• Fluorine Chemistry Research: An important substrate for studying structure-activity relationships (SAR) and novel fluorination reactions in academic and industrial R&D settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	Methyl 4-(2,6-Dimethylmorpholin-4-Yl)-2,3,5-Trifluorobenzoate
CAS No.	1858251-69-0
Molecular Formula	C14H15F3NO3
Molecular Weight	302.27 g/mol
Synonyms	4-(2,6-Dimethylmorpholin-4-yl)-2,3,5-trifluorobenzoic acid methyl ester; Methyl 2,3,5-trifluoro-4-(2,6-dimethylmorpholin-4-yl)benzoate; Benzoic acid, 4-(2,6-dimethyl-4-morpholinyl)-2,3,5-trifluoro-, methyl ester; 1858251-69-0; 2,3,5-Trifluoro-4-(2,6-dimethylmorpholino)benzoic acid methyl ester; Methyl 4-(2,6-dimethylmorpholino)-2,3,5-trifluorobenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(2,6-Dimethylmorpholin-4-Yl)-2,3,5-Trifluorobenzoate adheres to stringent quality management protocols. The material is manufactured under controlled conditions and undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support compliance with cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.