Description

5-Chloro-2-Fluoro-4-Hydroxybenzonitrile is a versatile halogenated benzonitrile derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring chloro, fluoro, and hydroxy substituents, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients. Its precise functionalization allows for the fine-tuning of biological activity and physicochemical characteristics in target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the halogen and nitrile groups contribute to bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, where its aromatic and polar structure can influence electro-optical properties.
• Organic Synthesis & Research: Employed in academic and industrial R&D for constructing complex aromatic systems, heterocycles, and as a scaffold for medicinal chemistry libraries.
• Polymer Modifier: Can be incorporated into polymer chains to impart specific characteristics like stability or reactivity.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments due to its substituted aromatic ring system.

Basic Information

Item	Detail
Product Name	5-Chloro-2-Fluoro-4-Hydroxybenzonitrile
CAS No.	1849382-33-7
Molecular Formula	C7H3ClFNO
Molecular Weight	171.56 g/mol
Synonyms	4-Hydroxy-5-chloro-2-fluorobenzonitrile; 2-Fluoro-4-hydroxy-5-chlorobenzonitrile; 5-Chloro-2-fluoro-4-hydroxybenzonitrile; Benzonitrile, 5-chloro-2-fluoro-4-hydroxy-; 1849382-33-7
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-4-Hydroxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.