Description

4-Amino-5-Fluoro-2-Methylbenzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring strategically placed amino, fluoro, and nitrile groups, makes it a versatile intermediate for constructing complex heterocyclic systems and functionalized aromatic compounds. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments due to its aromatic amine and nitrile functionality.
• Chemical Biology & Proteomics: Utilized as a building block for creating molecular probes, tags, and linkers in biochemical research and diagnostic assay development.

Basic Information

Product Name	4-Amino-5-Fluoro-2-Methylbenzonitrile
CAS No.	1849279-50-0
Molecular Formula	C8H7FN2
Molecular Weight	150.16 g/mol
Synonyms	5-Fluoro-2-methyl-4-aminobenzonitrile; 2-Methyl-4-amino-5-fluorobenzonitrile; 4-Amino-5-fluoro-o-tolunitrile; Benzonitrile, 4-amino-5-fluoro-2-methyl-; 5-Fluoro-4-amino-2-methylbenzonitrile; 2-Methyl-5-fluoro-4-aminobenzonitrile; 4-Amino-5-fluoro-2-methylbenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Fluoro-2-Methylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.