Description

5-Fluoro-Pyrrolo[2,3-C]Pyridine-1-Carboxylic Acid tert-Butyl Ester is a high-value, fluorinated heterocyclic building block essential for modern pharmaceutical research and development. Its core value lies in its role as a key synthetic intermediate for constructing complex molecules with potential biological activity. This compound is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged pyrrolopyridine scaffold.
• Agrochemical Development: Serves as a building block for creating new crop protection agents and herbicides with enhanced efficacy.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of complex molecules.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis providers offering specialized fluorinated compounds to client specifications.

Basic Information

Product Name	5-Fluoro-Pyrrolo[2,3-C]Pyridine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1841080-36-1
Molecular Formula	C12H13FN2O2
Molecular Weight	236.24 g/mol
Synonyms	1-Boc-5-Fluoropyrrolo[2,3-c]pyridine; 5-Fluoro-1H-pyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 5-fluoro-1H-pyrrolo[2,3-c]pyridine-1-carboxylate; 5-Fluoro-1-((tert-butoxy)carbonyl)-1H-pyrrolo[2,3-c]pyridine; 5-Fluoro-1H-pyrrolo[2,3-c]pyridine-1-carboxylic acid 1,1-dimethylethyl ester; 5-Fluoro-1-Boc-pyrrolo[2,3-c]pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-Pyrrolo[2,3-C]Pyridine-1-Carboxylic Acid tert-Butyl Ester undergoes rigorous analytical testing to ensure it meets the stringent purity and consistency standards required for advanced research and development. Our quality commitment includes comprehensive identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.