Description

Methyl 2-(2-Ethoxy-1,1-Difluoro-2-Oxoethyl)Benzoate is a specialized fluorinated benzoate ester derivative, serving as a high-value intermediate in advanced organic synthesis. Its core value lies in the strategic incorporation of difluoro and ethoxycarbonyl groups, which are critical for modulating the physicochemical properties and biological activity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules requiring specific fluorine substitution patterns.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting metabolic and central nervous system disorders where fluorine atoms enhance bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, where the difluoro moiety can improve lipophilicity and environmental persistence.
• Material Science Precursor: Serves as a monomer or modifier in the development of specialty polymers and coatings with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating novel ligands that can form complexes with transition metals for catalytic applications.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new C-F bond formation reactions and the development of fluorination methodologies.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex dyes, fragrances, and other high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	Methyl 2-(2-Ethoxy-1,1-Difluoro-2-Oxoethyl)Benzoate
CAS No.	1835726-67-4
Molecular Formula	C₁₂H₁₂F₂O₄
Molecular Weight	258.22 g/mol
Synonyms	Methyl 2-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoate; Benzoic acid, 2-(2-ethoxy-1,1-difluoro-2-oxoethyl)-, methyl ester; Methyl o-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoate; 2-(2-Ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid methyl ester; Difluoro Ethoxy Oxoethyl Benzoate Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(2-Ethoxy-1,1-Difluoro-2-Oxoethyl)Benzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR, IR, MS) techniques to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.