Description

2-(3,5-Dimethylphenyl)-2,2-Difluoroethan-1-Ol is a high-value fluorinated aromatic alcohol building block, prized for its unique structural motif that combines a substituted phenyl ring with a difluoroethanol moiety. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where the introduction of fluorine atoms is a key strategy to modulate biological activity, metabolic stability, and lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds for enhanced efficacy and pharmacokinetics.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the difluoro group can improve environmental stability and target specificity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and performance.
• Polymer & Resin Modifier: Incorporated as a monomer or additive to impart specific properties like chemical resistance, low surface energy, or altered refractive index to advanced polymers.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct complex fluorinated molecular architectures in academic and industrial research.

Basic Information

Product Name	2-(3,5-Dimethylphenyl)-2,2-Difluoroethan-1-Ol
CAS No.	1820687-72-6
Molecular Formula	C10H12F2O
Molecular Weight	186.20 g/mol
Synonyms	2,2-Difluoro-2-(3,5-dimethylphenyl)ethanol; 1-(3,5-Dimethylphenyl)-2,2-difluoroethan-1-ol; 2-(3,5-Dimethylphenyl)-2,2-difluoroethanol; α,α-Difluoro-3,5-dimethylbenzenemethanol; 3,5-Dimethyl-α,α-difluorobenzyl Alcohol
EINECS	Contact for details

Quality Control

Our 2-(3,5-Dimethylphenyl)-2,2-Difluoroethan-1-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under an inert atmosphere (nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.