Description

Benzonitrile, 2,3-Difluoro-5-Formyl- is a high-purity, multi-functional aromatic intermediate featuring a strategically positioned formyl group and fluorine atoms. This compound matters for its role as a critical building block in the synthesis of complex molecules, enabling the introduction of both aldehyde and nitrile functionalities for further derivatization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Used to create specialized ligands for transition metal catalysis and organocatalysts due to the electron-withdrawing nitrile and formyl groups.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of high-performance polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial labs.
• Fluorinated Fine Chemical Production: Intermediate for manufacturing other specialty fluorinated benzonitrile derivatives and fine chemicals.

Basic Information

Product Name	Benzonitrile, 2,3-Difluoro-5-Formyl-
CAS No.	1807274-74-3
Molecular Formula	C8H3F2NO
Molecular Weight	167.11 g/mol
Synonyms	2,3-Difluoro-5-formylbenzonitrile; 5-Cyano-2,3-difluorobenzaldehyde; 2,3-Difluoro-5-formylbenzonitrile; 2,3-Difluorobenzaldehyde-5-carbonitrile; 5-Formyl-2,3-difluorobenzonitrile; 2,3-Difluoro-5-cyanobenzaldehyde; Benzonitrile, 2,3-difluoro-5-formyl-; 1807274-74-3
EINECS	Contact for details

Quality Control

Our Benzonitrile, 2,3-Difluoro-5-Formyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.