Description

2-Bromo-1-Fluoro-5-Methyl-3-Nitro-Benzene is a high-purity halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought by research institutions and industrial manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty dyes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its halogen and nitro functional groups for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, including charge-transport layers and liquid crystal compounds for displays.
• Dye & Pigment Manufacturing: Intermediate for producing specialized azo dyes and nitro-aromatic pigments with enhanced lightfastness and color properties.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Research: Used in academic and industrial R&D for exploring new reaction pathways and synthesizing complex aromatic systems.

Basic Information

Product Name	2-Bromo-1-Fluoro-5-Methyl-3-Nitro-Benzene
CAS No.	1807212-21-0
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	1-Bromo-2-fluoro-4-methyl-6-nitrobenzene; 2-Bromo-1-fluoro-5-methyl-3-nitrobenzene; 3-Nitro-2-bromo-1-fluoro-5-methylbenzene; Benzene, 2-bromo-1-fluoro-5-methyl-3-nitro-; 1807212-21-0; 2-Bromo-1-fluoro-5-methyl-3-nitrobenzene (principal IUPAC name)
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Fluoro-5-Methyl-3-Nitro-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability and traceability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark environment. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.