Description

4,5-Difluoro-2-Formylbenzonitrile is a high-value, multi-functional aromatic building block featuring both a formyl and a nitrile group on a difluorinated benzene ring. This unique structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing electronic materials used in displays and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or optical properties.
• Chemical Research & Development: A versatile reagent for constructing complex heterocycles and fluorinated compounds in medicinal and synthetic chemistry.
• Coordination Chemistry Ligand: The formyl and nitrile groups can act as binding sites for metal ions in catalyst design.

Basic Information

Product Name	4,5-Difluoro-2-Formylbenzonitrile
CAS No.	1807177-35-0
Molecular Formula	C8H3F2NO
Molecular Weight	167.11 g/mol
Synonyms	2-Cyano-4,5-difluorobenzaldehyde; 4,5-Difluorophthalaldehyde nitrile; 4,5-Difluorobenzaldehyde-2-carbonitrile; Benzonitrile, 4,5-difluoro-2-formyl-; 2-Formyl-4,5-difluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-Formylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.