Description

1-Bromo-4-Fluoro-2-Iodo-5-Nitro-Benzene is a high-purity, multi-halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on novel active ingredients, materials science, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Serves as a precursor for organic electronic materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The iodine and bromine substituents make it an excellent substrate for Suzuki, Stille, and Sonogashira coupling reactions.
• Functional Dye & Pigment Development: Employed in the synthesis of specialized dyes and pigments with tailored optical properties.
• Chemical Biology & Proteomics: Can be used to create probes and tags for studying biological systems and protein interactions.

Basic Information

Product Name	1-Bromo-4-Fluoro-2-Iodo-5-Nitro-Benzene
CAS No.	1807173-61-0
Molecular Formula	C6H2BrFINO2
Molecular Weight	345.89 g/mol
Synonyms	4-Bromo-1-Fluoro-2-Iodo-5-Nitrobenzene; 2-Bromo-5-Fluoro-4-Iodo-1-Nitrobenzene; Benzene, 1-bromo-4-fluoro-2-iodo-5-nitro-; 5-Nitro-2-bromo-4-fluoro-1-iodobenzene; 1-Iodo-2-bromo-5-fluoro-4-nitrobenzene; 1807173-61-0; BRN 8230425
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Fluoro-2-Iodo-5-Nitro-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive and oxidizing nature, it should be stored separately from reducing agents and combustible materials. The container must be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.