Description

1-Bromo-4-Nitro-2-Trifluoromethoxy-Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique trifluoromethoxy and nitro substituents, which impart significant electronic and steric properties, making it a critical intermediate in the development of complex molecules. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in drug discovery, crop protection, and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethoxy group.
• Ligand and Catalyst Development: Serves as a sophisticated building block for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing character.
• Fluorine Chemistry: An essential substrate for further functionalization in fluorine chemistry, enabling the introduction of additional fluorinated motifs.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-complexity intermediates.

Basic Information

Product Name	1-Bromo-4-Nitro-2-Trifluoromethoxy-Benzene
CAS No.	1807109-20-1
Molecular Formula	C7H3BrF3NO3
Molecular Weight	285.99 g/mol
Synonyms	2-Bromo-5-nitro-1-(trifluoromethoxy)benzene; 4-Nitro-2-(trifluoromethoxy)bromobenzene; 1-Bromo-4-nitro-2-(trifluoromethoxy)benzene; Benzene, 1-bromo-4-nitro-2-(trifluoromethoxy)-; 2-Trifluoromethoxy-4-nitro-1-bromobenzene; 5-Nitro-2-(trifluoromethoxy)bromobenzene; 2-Bromo-5-nitro-α,α,α-trifluoroanisole
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Nitro-2-Trifluoromethoxy-Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.