Description

2-Fluoro-4,5-Dibromonitrobenzene is a high-value, multi-functional halogenated aromatic building block. Its unique structure, featuring fluorine, bromine, and nitro substituents, makes it a critical intermediate for synthesizing complex molecules with tailored electronic and steric properties. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine and bromine atoms can enhance binding affinity and environmental persistence.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atoms are excellent handles for palladium-catalyzed reactions (e.g., Suzuki, Heck, Buchwald-Hartwig), enabling rapid diversification of the molecular scaffold.
• Nitro Group Reduction: The nitro functionality can be selectively reduced to an amine, providing a versatile pathway to diamino-dibromo-fluorobenzene derivatives for further chemical elaboration.
• Fluorine Chemistry Studies: A valuable substrate for investigating the influence of fluorine substitution on reaction kinetics and molecular conformation in aromatic systems.

Basic Information

Product Name	2-Fluoro-4,5-Dibromonitrobenzene
CAS No.	1807056-85-4
Molecular Formula	C6H2Br2FNO2
Molecular Weight	298.89 g/mol
Synonyms	1,2-Dibromo-4-fluoro-5-nitrobenzene; 4,5-Dibromo-2-fluoronitrobenzene; Benzene, 1,2-dibromo-4-fluoro-5-nitro-; 2-Fluoro-1,2-dibromo-5-nitrobenzene; 5-Nitro-1,2-dibromo-4-fluorobenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4,5-Dibromonitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed and stored in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.