Description

1-Bromo-3-Fluoro-2-Methyl-4-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity and stability.
• Material Science Precursor: Serves as a building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex organic dyes and pigments, leveraging the nitro and halogen groups for color tuning and fastness.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to create biaryl and other complex structures.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and for creating compound libraries in drug discovery programs.

Basic Information

Product Name	1-Bromo-3-Fluoro-2-Methyl-4-Nitrobenzene
CAS No.	1806979-60-1
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	2-Bromo-6-Fluoro-3-Nitrotoluene; 3-Bromo-1-Fluoro-2-Methyl-4-Nitrobenzene; 4-Nitro-1-Bromo-3-Fluoro-2-Methylbenzene; Benzene, 1-bromo-3-fluoro-2-methyl-4-nitro-; 1806979-60-1; 2-Methyl-3-fluoro-6-nitrobenzene bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Fluoro-2-Methyl-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.