Description

1,3-Dimethoxy-5-Fluoro-2-Nitrobenzene is a high-purity, multi-functional aromatic intermediate designed for advanced chemical synthesis. This compound is valued for its unique substitution pattern, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty agrochemicals, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine and nitro groups for enhanced biological activity and selectivity.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro group and methoxy substituents.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and organic pigments where specific color and stability properties are required.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures.
• Chemical Library Development: Utilized in combinatorial chemistry and high-throughput screening for generating diverse compound libraries in drug discovery programs.

Basic Information

Item	Details
Product Name	1,3-Dimethoxy-5-Fluoro-2-Nitrobenzene
CAS No.	1806452-66-3
Molecular Formula	C8H8FNO4
Molecular Weight	201.15 g/mol
Synonyms	5-Fluoro-1,3-dimethoxy-2-nitrobenzene; 2-Nitro-5-fluoro-1,3-dimethoxybenzene; 1,3-Dimethoxy-5-fluoronitrobenzene; 5-Fluoro-2-nitroresorcinol dimethyl ether; 3,5-Dimethoxy-4-fluoronitrobenzene; Benzene, 1,3-dimethoxy-5-fluoro-2-nitro-; FNO-235 (common research code)
EINECS	Contact for details

Quality Control

Our 1,3-Dimethoxy-5-Fluoro-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, GC, NMR, and other relevant analytical techniques to confirm compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.