Description

2,5-Dibromo-3-Fluorobenzonitrile is a halogenated benzonitrile derivative, a versatile and high-value organic intermediate. Its unique structure, featuring bromine and fluorine substituents, makes it a critical building block for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the dibromo-fluorobenzonitrile scaffold contributes to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its ability to modify molecular polarity and conjugation.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to construct complex biaryl systems for various high-value applications.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2,5-Dibromo-3-Fluorobenzonitrile
CAS No.	1806353-46-7
Molecular Formula	C7H2Br2FN
Molecular Weight	278.90 g/mol
Synonyms	3-Fluoro-2,5-dibromobenzonitrile; 2,5-Dibromo-3-fluorobenzonitrile; Benzonitrile, 2,5-dibromo-3-fluoro-; 1806353-46-7
EINECS	Contact for details

Quality Control

Our 2,5-Dibromo-3-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.