Description

2,6-Difluoro-3-(trifluoromethyl)benzonitrile is a high-value, multi-fluorinated aromatic nitrile building block. This compound matters for its role as a critical intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where its unique fluorine substitution pattern imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging fluorine's effects on lipophilicity and target binding.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas requiring enhanced bioavailability and receptor selectivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for fluorine-containing aromatic cores used in electronic display technologies and organic semiconductors.
• Polymer Modification: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Cross-Coupling Reactions: The nitrile and halogen groups make it a versatile substrate for Suzuki, Buchwald-Hartwig, and other metal-catalyzed coupling reactions.
• Fluorine Chemistry Research: An important compound for academic and industrial research into the synthesis and properties of polyfluorinated aromatic systems.

Basic Information

Product Name	2,6-Difluoro-3-(trifluoromethyl)benzonitrile
CAS No.	1806333-92-5
Molecular Formula	C8H2F5N
Molecular Weight	207.10 g/mol
Synonyms	3-(Trifluoromethyl)-2,6-difluorobenzonitrile; 2,6-Difluoro-α,α,α-trifluoro-m-toluonitrile; 2,6-Difluoro-3-trifluoromethylbenzonitrile; Benzonitrile, 2,6-difluoro-3-(trifluoromethyl)-; 2,6-Difluoro-α,α,α-trifluoro-m-tolunitrile
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-(trifluoromethyl)benzonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.