Description

1,2-Dichloro-5-Fluoro-3-Nitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides specific reactivity for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing fluorine for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and nitro groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Dye and Pigment Manufacturing: Intermediate for creating complex, halogenated organic dyes and pigments with specific color fastness and properties.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures common in many functional molecules.

Basic Information

Product Name	1,2-Dichloro-5-Fluoro-3-Nitrobenzene
CAS No.	1806280-44-3
Molecular Formula	C6H2Cl2FNO2
Molecular Weight	209.99 g/mol
Synonyms	3-Nitro-1,2-dichloro-5-fluorobenzene; 1,2-Dichloro-5-fluoronitrobenzene; 5-Fluoro-1,2-dichloro-3-nitrobenzene; 2,3-Dichloro-4-fluoronitrobenzene; Benzene, 1,2-dichloro-5-fluoro-3-nitro-; 1806280-44-3 (CAS)
EINECS	Contact for details

Quality Control

Our 1,2-Dichloro-5-Fluoro-3-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.