Description

4-Bromo-5-Fluoro-2-Hydroxybenzonitrile is a high-purity, multi-functional halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine, fluorine, and a nitrile group on a phenolic ring, makes it an exceptionally versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen atoms contribute to bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing and steric properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	4-Bromo-5-Fluoro-2-Hydroxybenzonitrile
CAS No.	1805936-02-0
Molecular Formula	C7H3BrFNO
Molecular Weight	216.01 g/mol
Synonyms	2-Hydroxy-4-bromo-5-fluorobenzonitrile; 4-Bromo-5-fluoro-2-hydroxybenzonitrile; 5-Fluoro-4-bromo-2-hydroxybenzonitrile; 2-Cyano-4-bromo-5-fluorophenol; Benzonitrile, 4-bromo-5-fluoro-2-hydroxy-; 1805936-02-0
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-5-Fluoro-2-Hydroxybenzonitrile is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in secondary opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.