Description

1,2-Dibromo-3-Fluoro-4-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block. This compound is valued for its unique reactivity profile, where the strategic placement of bromine, fluorine, and nitro groups enables selective functionalization for complex molecular synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Cross-Coupling Reactions: The bromine substituents make it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination to build complex biaryl structures.
• Nucleophilic Aromatic Substitution: The activated nitro and fluorine groups allow for selective displacement reactions, facilitating the introduction of various nucleophiles.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in related chemical processes.

Basic Information

Product Name	1,2-Dibromo-3-Fluoro-4-Nitrobenzene
CAS No.	1805123-35-6
Molecular Formula	C6H2Br2FNO2
Molecular Weight	298.89 g/mol
Synonyms	3-Fluoro-1,2-dibromo-4-nitrobenzene; 4-Nitro-1,2-dibromo-3-fluorobenzene; 1,2-Dibromo-3-fluoro-4-nitro-benzene; Benzene, 1,2-dibromo-3-fluoro-4-nitro-; 1805123-35-6 (CAS); DBFN
EINECS	Contact for details

Quality Control

Our 1,2-Dibromo-3-Fluoro-4-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.