Description

4,5-Dibromo-2-Fluorobenzonitrile is a high-purity fluorinated and brominated aromatic nitrile building block. This compound is valued for its unique halogen substitution pattern, which makes it a versatile intermediate in advanced organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine and bromine atoms for bioactivity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitrile group and halogen atoms.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Buchwald-Hartwig) to introduce complex aromatic systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	4,5-Dibromo-2-Fluorobenzonitrile
CAS No.	1804932-62-4
Molecular Formula	C7H2Br2FN
Molecular Weight	280.90 g/mol
Synonyms	2-Fluoro-4,5-dibromobenzonitrile; 4,5-Dibromo-2-fluorobenzonitrile; Benzonitrile, 4,5-dibromo-2-fluoro-; 2-Fluoro-4,5-dibromobenzene carbonitrile; 4,5-Dibromo-2-fluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our 4,5-Dibromo-2-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.