Description

2-Nutro-4-Fluoro-5-Cyanotoulene is a high-purity, multi-functional aromatic intermediate designed for advanced chemical synthesis. This compound is valued for its unique combination of nitro, fluoro, and cyano functional groups, which provide versatile reactivity for constructing complex molecular architectures. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, crop protection, and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the nitro and cyano groups.
• Material Science Research: Serves as a precursor for advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Dye and Pigment Industry: Intermediate for manufacturing specialized azo dyes and pigments where the cyano and nitro groups influence color and stability.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures common in many functional molecules.

Basic Information

Product Name	2-Nutro-4-Fluoro-5-Cyanotoulene
CAS No.	1803852-84-7
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	2-Nitro-4-fluoro-5-cyanotoluene; 5-Cyano-2-nitro-4-fluorotoluene; 4-Fluoro-5-cyano-2-nitrotoluene; 2-Nitro-4-fluoro-5-methylbenzonitrile; Toluene, 2-nitro-4-fluoro-5-cyano-; 1803852-84-7; 2-Nitro-4-fluoro-5-cyanomethylbenzene (common name)
EINECS	Contact for details

Quality Control

Our 2-Nutro-4-Fluoro-5-Cyanotoulene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.