Description

3,4-Difluoro-5-Methylbenzonitrile is a high-purity fluorinated aromatic nitrile building block. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, particularly in the development of complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring difluoromethyl or trifluoromethyl motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials.
• Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine into polymer backbones, altering material properties like chemical resistance and thermal stability.
• General Organic Synthesis: A versatile building block for constructing complex aromatic systems via reactions like Suzuki coupling, cyano group transformations, and nucleophilic aromatic substitution.

Basic Information

Product Name	3,4-Difluoro-5-Methylbenzonitrile
CAS No.	1803833-51-3
Molecular Formula	C8H5F2N
Molecular Weight	153.13 g/mol
Synonyms	5-Methyl-3,4-difluorobenzonitrile; 3,4-Difluoro-5-methylbenzonitrile; Benzonitrile, 3,4-difluoro-5-methyl-; 2,3-Difluoro-6-cyanotoluene
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-5-Methylbenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.