Description

2,4-Difluoro-6-Methylbenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its difluoromethyl-substituted benzene core introduces desirable metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a versatile, fluorinated aromatic moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for advanced display technologies.
• Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with enhanced chemical resistance and thermal stability.
• Organic Electronic Materials: Employed in the synthesis of electron-transport materials and semiconductors for OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent for exploring new fluorination reactions and constructing complex heterocyclic systems in academic and industrial labs.

Basic Information

Product Name	2,4-Difluoro-6-Methylbenzonitrile
CAS No.	1803782-57-1
Molecular Formula	C8H5F2N
Molecular Weight	153.13 g/mol
Synonyms	2,4-Difluoro-6-methylbenzonitrile; 6-Methyl-2,4-difluorobenzonitrile; 2,4-Difluoro-6-methyl-benzonitrile; Benzonitrile, 2,4-difluoro-6-methyl-; 2,4-Difluoro-6-methylbenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-6-Methylbenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.