Description

3-(2-Fluoro-4-Methoxyphenyl)Propanenitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an electron-donating methoxy group and a fluorine atom, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials due to its fluorinated aromatic core.
• Functional Polymer Monomer: Acts as a specialty monomer for creating polymers with specific optical, electronic, or surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create biaryl systems.

Basic Information

Product Name	3-(2-Fluoro-4-Methoxyphenyl)Propanenitrile
CAS No.	1803727-00-5
Molecular Formula	C₁₀H₁₀FNO
Molecular Weight	179.19 g/mol
Synonyms	2-Fluoro-4-methoxyhydrocinnamontrile; 3-(2-Fluoro-4-methoxyphenyl)propionitrile; (2-Fluoro-4-methoxyphenyl)propanenitrile; 3-(2-Fluoro-4-methoxyphenyl)propanenitrile; β-(2-Fluoro-4-methoxyphenyl)propionitrile; 2-Fluoro-4-methoxy-β-phenylpropionitrile; 1803727-00-5; FMPPN
EINECS	Contact for details

Quality Control

Our production of 3-(2-Fluoro-4-Methoxyphenyl)Propanenitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.