Description

2-Fluoro-1-Methoxymethyl-4-Nitro-Benzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate, offering a unique combination of reactive nitro and methoxymethyl groups on a fluorinated benzene ring, enabling precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those requiring fluorinated aromatic scaffolds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The nitro and halogen groups make it a suitable substrate for various palladium-catalyzed coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Functional Group Transformation: Used in laboratories for studying reduction reactions of nitro groups and ether manipulations.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Fluoro-1-Methoxymethyl-4-Nitro-Benzene
CAS No.	1803607-63-7
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	1-(Fluoromethyl)-2-methoxy-5-nitrobenzene; 2-Fluoro-1-(methoxymethyl)-4-nitrobenzene; 4-Nitro-2-fluoro-1-(methoxymethyl)benzene; Benzene, 2-fluoro-1-(methoxymethyl)-4-nitro-; 2-Fluoro-α-(methoxymethyl)-4-nitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-1-Methoxymethyl-4-Nitro-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.