Description

2-Chloro Clomiphene Citrate (E/Z Mixture) is a chemically modified derivative of the selective estrogen receptor modulator (SERM) clomiphene citrate, distinguished by the addition of a chlorine substituent. This modification is of significant interest in pharmaceutical research for developing novel therapeutic agents and exploring structure-activity relationships. It serves as a critical pharmaceutical intermediate and reference standard for researchers and developers in the life sciences sector.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of novel SERM-based therapeutics.
• Biochemical Research: Used in studies investigating estrogen receptor binding affinity, antagonism, and downstream biological effects.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Metabolite Studies: Employed in the synthesis and identification of potential metabolites for pharmacokinetic and safety profiling.
• Academic & Contract Research: Essential material for university laboratories and CROs (Contract Research Organizations) focused on endocrinology and oncology research.

Basic Information

Product Name	2-Chloro Clomiphene Citrate (E/Z Mixture)
CAS No.	1795130-18-5
Molecular Formula	C32H36ClNO8 • C6H8O7
Molecular Weight	Contact for details
Synonyms	2-Chloro Clomiphene Citrate
2-Chloro Clomiphene Citrate (E/Z Isomer Mixture)
2-Chloro-2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
2-Chloro Zu Clomiphene Citrate
Clomiphene Citrate, 2-Chloro Derivative
2-Chloro Clomifene Citrate
Research Compound 1795130-18-5
EINECS	Contact for details

Quality Control

Our 2-Chloro Clomiphene Citrate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and isomer ratio determination, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and all relevant specifications is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
E/Z Isomer Ratio	Specified on COA
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.