Description

5-Bromo-4-Fluoro-1-Methyl-1H-Indazole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its precise bromo-fluoro substitution pattern on the indazole scaffold, which is critical for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents, leveraging the halogenated indazole core for bioactivity.
• Material Science: Serves as a precursor for functionalized organic materials and ligands for metal-organic frameworks (MOFs) or catalysts.
• Chemical Biology: Employed as a molecular probe or a tagged building block in proteolysis-targeting chimeras (PROTACs) and other chemical biology tools.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, halogenated heterocycles.

Basic Information

Product Name	5-Bromo-4-Fluoro-1-Methyl-1H-Indazole
CAS No.	1784678-61-0
Molecular Formula	C8H6BrFN2
Molecular Weight	229.05 g/mol
Synonyms	1-Methyl-5-bromo-4-fluoro-1H-indazole; 5-Bromo-4-fluoro-1-methylindazole; 1H-Indazole, 5-bromo-4-fluoro-1-methyl-; 1784678-61-0; 5-Br-4-F-1-Me-1H-Indazole
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoro-1-Methyl-1H-Indazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.