Description

2-(3,4-Dimethylphenyl)-2,2-Difluoroethan-1-Ol is a high-value fluorinated organic building block characterized by its difluoroethanol moiety attached to a dimethylphenyl ring. This compound is essential for advanced chemical synthesis, where its unique structure enables the introduction of fluorine atoms to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where fluorine substitution can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing specialty polymers and liquid crystals with tailored properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct complex fluorinated architectures.
• Fluorine Chemistry Studies: A valuable reference compound for academic and industrial research into the behavior of difluoroalkylarenes.

Basic Information

Item	Detail
Product Name	2-(3,4-Dimethylphenyl)-2,2-Difluoroethan-1-Ol
CAS No.	1780791-11-8
Molecular Formula	C10H12F2O
Molecular Weight	186.20 g/mol
Synonyms	2,2-Difluoro-2-(3,4-dimethylphenyl)ethanol; 1-(3,4-Dimethylphenyl)-2,2-difluoroethan-1-ol; α,α-Difluoro-3,4-dimethylphenethyl alcohol; 2-(3,4-Dimethylphenyl)-2,2-difluoroethanol; 3,4-Dimethyl-α,α-difluorobenzeneethanol
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dimethylphenyl)-2,2-Difluoroethan-1-Ol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid or clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.