Description

3,4-Dichloro-5-(Trifluoromethoxy)Phenylacetonitrile is a high-value, multi-functional aromatic nitrile building block. This compound is critical for the synthesis of advanced agrochemicals and pharmaceuticals due to its unique combination of halogen and trifluoromethoxy substituents, which impart desirable biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and intermediates.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the dichloro-trifluoromethoxy motif.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas targeting central nervous system (CNS) disorders and inflammatory diseases.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and liquid crystals where specific halogenated aromatic units are required.
• Custom Synthesis and Contract Manufacturing: A vital intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3,4-Dichloro-5-(Trifluoromethoxy)Phenylacetonitrile
CAS No.	1706458-58-3
Molecular Formula	C9H4Cl2F3NO
Molecular Weight	270.04 g/mol
Synonyms	2-(3,4-Dichloro-5-(trifluoromethoxy)phenyl)acetonitrile; (3,4-Dichloro-5-(trifluoromethoxy)phenyl)acetonitrile; 3,4-Dichloro-5-(trifluoromethoxy)benzyl cyanide; 1706458-58-3; α-Cyano-3,4-dichloro-5-(trifluoromethoxy)toluene; 2-(3,4-Dichloro-5-((trifluoromethyl)oxy)phenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-5-(Trifluoromethoxy)Phenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.