Description

2-Fluoro-5-Methyl-3-(Trifluoromethyl)Phenylacetonitrile is a high-value fluorinated aromatic nitrile building block. This compound is critical for introducing specific steric and electronic properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and CNS-targeting drugs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, leveraging the trifluoromethyl group for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or surface properties.
• Chemical Research & Development: A versatile building block in medicinal chemistry and material science for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring precise fluorination patterns.

Basic Information

Product Name	2-Fluoro-5-Methyl-3-(Trifluoromethyl)Phenylacetonitrile
CAS No.	1706438-79-0
Molecular Formula	C10H7F4N
Molecular Weight	217.16 g/mol
Synonyms	2-Fluoro-5-methyl-3-(trifluoromethyl)benzyl cyanide; [2-Fluoro-5-methyl-3-(trifluoromethyl)phenyl]acetonitrile; α-(2-Fluoro-5-methyl-3-(trifluoromethyl)phenyl)acetonitrile; 2-Fluoro-α,α,α,5-tetramethylbenzenepropanenitrile; 1706438-79-0; (2-Fluoro-5-methyl-3-(trifluoromethyl)phenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methyl-3-(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.