Description

3-Butoxy-2,6-Difluorophenylacetonitrile is a specialized fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an alkoxy and a nitrile group on a difluorinated benzene ring, makes it a valuable precursor for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries. It serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on fluoroorganic chemistry and cross-coupling reactions.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3-Butoxy-2,6-Difluorophenylacetonitrile
CAS No.	1706435-04-2
Molecular Formula	C₁₂H₁₃F₂NO
Molecular Weight	225.24 g/mol
Synonyms	2-(3-Butoxy-2,6-difluorophenyl)acetonitrile; (3-Butoxy-2,6-difluorophenyl)acetonitrile; 2,6-Difluoro-3-butoxyphenylacetonitrile; α-Cyano-3-butoxy-2,6-difluorotoluene; 1706435-04-2; 3-n-Butoxy-2,6-difluorobenzyl cyanide; Butoxy-difluoro-phenylacetonitrile
EINECS	Contact for details

Quality Control

Our 3-Butoxy-2,6-Difluorophenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, identity, and impurity profiles. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be hygroscopic; handle under dry conditions to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.