Description

4-Methoxy-3-Methyl-5-(Trifluoromethyl)-Phenylacetonitrile is a high-value, multi-functional aromatic nitrile building block characterized by its methoxy, methyl, and trifluoromethyl substituents. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique substitution pattern enables precise molecular design and optimization. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring trifluoromethylated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers or functional units for advanced polymers and organic electronic materials.
• Fluorine Chemistry Building Block: A valuable starting material for further functionalization in medicinal and discovery chemistry programs focused on fluorine incorporation.

Basic Information

Product Name	4-Methoxy-3-Methyl-5-(Trifluoromethyl)-Phenylacetonitrile
CAS No.	1706430-20-7
Molecular Formula	C11H10F3NO
Molecular Weight	229.20 g/mol
Synonyms	2-(4-Methoxy-3-methyl-5-(trifluoromethyl)phenyl)acetonitrile; [4-Methoxy-3-methyl-5-(trifluoromethyl)phenyl]acetonitrile; 4-Methoxy-3-methyl-5-(trifluoromethyl)benzeneacetonitrile; 2-(4-Methoxy-3-methyl-5-(trifluoromethyl)phenyl)ethanenitrile; α-(4-Methoxy-3-methyl-5-(trifluoromethyl)phenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-Methyl-5-(Trifluoromethyl)-Phenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.