Description

2-(1,1-Difluoroethyl)Benzonitrile is a high-value, fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoroethyl group adjacent to the benzonitrile moiety, enabling precise molecular modifications. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and CNS-active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a precursor for fluorinated aromatic cores in electronic and optoelectronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution to introduce the difluoroethylbenzene unit.
• Fluorine Chemistry Research: A valuable substrate for studying the effects of gem-difluoro groups on aromatic system reactivity and physical properties.

Basic Information

Product Name	2-(1,1-Difluoroethyl)Benzonitrile
CAS No.	1706430-09-2
Molecular Formula	C9H7F2N
Molecular Weight	167.16 g/mol
Synonyms	2-(1,1-Difluoroethyl)benzonitrile; 2-(1,1-Difluoroethyl)phenyl cyanide; α,α-Difluoroethylbenzonitrile; o-(1,1-Difluoroethyl)benzonitrile; Benzonitrile, 2-(1,1-difluoroethyl)-; 1-(2-Cyanophenyl)-1,1-difluoroethane; 1706430-09-2 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 2-(1,1-Difluoroethyl)Benzonitrile is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.