Description

(R)-4-((S)-1-Fluoroethyl)Oxazolidin-2-One CAS NO 1628810-07-0 is a high-purity, chiral oxazolidinone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique stereochemistry and fluorine substitution, which are essential for modulating the biological activity and metabolic stability of target molecules. This compound is primarily needed by pharmaceutical R&D and process chemistry teams for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug candidates.
• API Development: Used in research and process development for new fluorinated pharmaceuticals.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Catalysis: Can be employed as an auxiliary or ligand precursor in stereoselective transformations.
• Process Chemistry: Used in scale-up and route scouting for the commercial manufacturing of enantiopure drugs.
• Chemical Biology: Useful as a probe or labeled compound in biochemical and pharmacological research.

Basic Information

Item	Detail
Product Name	(R)-4-((S)-1-Fluoroethyl)Oxazolidin-2-One
CAS No.	1628810-07-0
Molecular Formula	C5H8FNO2
Molecular Weight	133.12 g/mol
Synonyms	(R)-4-[(S)-1-Fluoroethyl]-2-oxazolidinone; (4R)-4-[(1S)-1-Fluoroethyl]-1,3-oxazolidin-2-one; (R)-4-((S)-1-Fluoroethyl)oxazolidin-2-one; (R)-4-[(S)-1-Fluoroethyl]-2-oxazolidinone; (4R,1'S)-4-(1'-Fluoroethyl)-2-oxazolidinone; Fluorinated Oxazolidinone Chiral Auxiliary; (R,S)-Fluoroethyl Oxazolidinone
EINECS	Contact for details

Quality Control

Our (R)-4-((S)-1-Fluoroethyl)Oxazolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.