Description

5-Chloro-2,3-Difluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block, essential for advanced organic synthesis. This compound is valued for its unique halogenated structure, which enables precise molecular modifications in the development of complex active ingredients. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for creating novel compounds, including active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used as a core building block for developing new-generation herbicides and fungicides with enhanced efficacy.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and material science.
• Functional Material Research: Employed in the research and development of liquid crystals, organic semiconductors, and advanced polymers.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Chloro-2,3-Difluorobenzonitrile
CAS No.	1624261-31-9
Molecular Formula	C7H2ClF2N
Molecular Weight	173.55 g/mol
Synonyms	2,3-Difluoro-5-chlorobenzonitrile; Benzonitrile, 5-chloro-2,3-difluoro-; 5-Chloro-2,3-difluorobenzene carbonitrile; 1624261-31-9; 5-Chloro-2,3-difluoro-benzonitrile
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,3-Difluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring material traceability and consistency for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.