Description

Abiraterone Propionate is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) derivative of abiraterone. This compound is critical for research and development in advanced oncology therapeutics, offering a key building block for targeted drug synthesis. It is primarily utilized by pharmaceutical manufacturers, research institutions, and CDMOs (Contract Development and Manufacturing Organizations) focused on developing next-generation treatments for hormone-sensitive cancers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of abiraterone acetate, a vital API for prostate cancer treatment.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action and develop novel anti-cancer agents.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Drug Discovery & Development: A crucial component in medicinal chemistry programs aimed at creating new steroidal CYP17A1 inhibitors.
• GMP Manufacturing: Supplied as a starting material for the production of finished dosage forms under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	Abiraterone Propionate
CAS No.	1620323-43-4
Molecular Formula	C₂₆H₃₃NO₂
Molecular Weight	391.55 g/mol
Synonyms	(3S,8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl propionate; 17-(3-Pyridyl)androsta-5,16-dien-3β-ol propionate; Abiraterone 3-propionate
EINECS	Contact for details

Quality Control

Our Abiraterone Propionate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. The product is tested against rigorous in-house specifications, which are aligned with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.