Description

1H-Pyrrole-2,5-Dione, 1-[3-[2-[(11β,16α)-9-Fluoro-11,17,21-Trihydroxy-16-Methyl-3-Oxopregna-1,4-Dien-20-Ylidene]Hydrazinyl]Propyl]- is a high-purity, structurally complex organic compound designed for advanced research and development. This compound is of significant interest for its potential as a key synthetic intermediate or active pharmaceutical ingredient (API) derivative in the development of novel therapeutic agents. It is primarily targeted at pharmaceutical R&D laboratories, biotechnology firms, and academic institutions engaged in cutting-edge medicinal chemistry and steroid-based drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel steroid-based drug candidates, particularly those targeting inflammatory or hormonal pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new chemical entities with potential therapeutic benefits.
• Bioconjugation & Prodrug Development: The reactive pyrrole-2,5-dione moiety can be utilized for conjugation with biomolecules or to create prodrug formulations.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Tool Compound: Used in preclinical research to investigate specific biological mechanisms and receptor interactions.
• Advanced Organic Synthesis: Acts as a specialized reagent for constructing complex molecular architectures in academic and industrial research settings.

Basic Information

Product Name	1H-Pyrrole-2,5-Dione, 1-[3-[2-[(11β,16α)-9-Fluoro-11,17,21-Trihydroxy-16-Methyl-3-Oxopregna-1,4-Dien-20-Ylidene]Hydrazinyl]Propyl]-
CAS No.	1618096-56-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 20-hydrozone with 1-(3-hydrazinylpropyl)-1H-pyrrole-2,5-dione; Dexamethasone derivative hydrazone; Dexamethasone pyrrole-2,5-dione conjugate; 1-(3-(2-(9-Fluoro-11β,17,21-trihydroxy-16α-methyl-3-oxopregna-1,4-dien-20-ylidene)hydrazinyl)propyl)-1H-pyrrole-2,5-dione; Steroid-pyrrole-dione conjugate; CAS 1618096-56-2.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We adhere to strict quality management protocols suitable for research and pharmaceutical-grade materials. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Specifications are developed with reference to ICH guidelines for impurities and stability, ensuring data integrity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.