Description

1,5-Difluoro-3-Methyl-2-Nitrobenzene is a high-purity, multi-functional aromatic building block designed for advanced organic synthesis. This compound matters for its unique substitution pattern, offering a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated and nitrated aromatic cores.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides where the difluoro and nitro groups confer specific biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology & Proteomics: Employed as a tagging or cross-linking reagent due to its reactive nitro group, which can be further reduced or substituted.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex fluorinated dyes and pigments with enhanced stability and color properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for bespoke synthesis projects requiring high-quality, well-defined fluorinated intermediates.

Basic Information

Product Name	1,5-Difluoro-3-Methyl-2-Nitrobenzene
CAS No.	1616526-80-7
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	2-Nitro-1,5-difluoro-3-methylbenzene; 3-Methyl-2,6-difluoronitrobenzene; 1,5-Difluoro-3-methyl-2-nitro-benzene; Benzene, 1,5-difluoro-3-methyl-2-nitro-; 2,6-Difluoro-3-methylnitrobenzene
EINECS	Contact for details

Quality Control

Our 1,5-Difluoro-3-Methyl-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.