Description

1-(Benzyloxy)-3-Fluoro-5-Nitrobenzene is a high-purity fluorinated nitroaromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a benzyl-protected phenol, a fluorine substituent, and a nitro group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, pesticides, and fungicides where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Ligand & Catalyst Development: Employed in the preparation of complex ligands for catalysis and molecular recognition studies.
• Chemical Synthesis: Utilized in various organic transformations, including nucleophilic aromatic substitution (SNAr) reactions facilitated by the fluorine and nitro groups.
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in university laboratories and corporate R&D centers focused on fluoroorganic chemistry.

Basic Information

Product Name	1-(Benzyloxy)-3-Fluoro-5-Nitrobenzene
CAS No.	1536920-33-8
Molecular Formula	C13H10FNO3
Molecular Weight	247.22 g/mol
Synonyms	3-Fluoro-5-nitrobenzylbenzene ether; Benzene, 1-(benzyloxy)-3-fluoro-5-nitro-; 3-Fluoro-5-nitro phenyl benzyl ether; 1-Fluoro-3-(benzyloxy)-5-nitrobenzene; 5-Nitro-3-fluorophenyl benzyl ether; 3-Fluoro-5-nitrophenyl benzyl ether; (3-Fluoro-5-nitrophenoxy)methyl]benzene
EINECS	Contact for details

Quality Control

Every batch of 1-(Benzyloxy)-3-Fluoro-5-Nitrobenzene is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications, which are aligned with industry best practices for fine chemical intermediates. A detailed Certificate of Analysis (COA) documenting purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere for long-term storage). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.